Real-time phase-contrast x-ray imaging: a new technique for the study of animal form and function.

ABSTRACT:

Background

Despite advances in imaging techniques, real-time visualization of the structure and dynamics of tissues and organs inside small living animals has remained elusive. Recently, we have been using synchrotron x-rays to visualize the internal anatomy of millimeter-sized opaque, living animals. This technique takes advantage of partially-coherent x-rays and diffraction to enable clear visualization of internal soft tissue not viewable via conventional absorption radiography. However, because higher quality images require greater x-ray fluxes, there exists an inherent tradeoff between image quality and tissue damage.

Results

We evaluated the tradeoff between image quality and harm to the animal by determining the impact of targeted synchrotron x-rays on insect physiolo

SUBMITTER: Socha JJ 

PROVIDER: S-EPMC1831761 | biostudies-literature | 2007 Mar

REPOSITORIES: biostudies-literature