Resting state cortical connectivity reflected in EEG coherence in individuals with autism.

ABSTRACT:

Background

Theoretical conceptions of autism spectrum disorder (ASD) and experimental studies of cerebral blood flow suggest abnormalities in connections among distributed neural systems in ASD.

Methods

Functional connectivity was assessed with electroencephalographic coherence between pairs of electrodes in a high-density electrode array in narrow frequency bands among 18 adults with ASD and 18 control adults in an eyes closed resting state.

Results

In the theta (3-6 Hz) frequency range, locally elevated coherence was evident for the ASD group, especially within left hemisphere frontal and temporal regions. In the lower alpha range (8-10 Hz), globally reduced coherence was evident for the ASD group within frontal regions and between frontal and all other scalp region

SUBMITTER: Murias M 

PROVIDER: S-EPMC2001237 | biostudies-literature | 2007 Aug

REPOSITORIES: biostudies-literature