Dataset Information
Morphologic and histologic outcomes of tongue reduction surgery in an animal model.
Ontology highlight
ABSTRACT: Objective
To describe the effect of anterior tongue reduction surgery on tongue size, morphology, and histology.Design
Prospective experiment.Materials
Twenty-two 12-week-old Yucatan minipigs.Methods
Six sibling pairs had tongue reduction (Group B) or sham surgery (Group A), and underwent euthanasia the day of surgery. Five sibling pairs had tongue reduction (Group D) or sham surgery (Group C), and were raised for four weeks. Data collected included changes in tongue morphology, histology, and animal response to surgery.Results
All animals tolerated surgery and maintained their weight. Tongue size was uniformly reduced in all animals as compared to sham surgery. Tongue reduction was stable long term in Group D. All animals had normal wound healing and neurovascular structure preservation. Fibrosis occurred at the repair site.Conclusion
Midline tongue reduction resulted in uniform tongue reduction in all dimensions and volume, without damaging neurovascular structures. Localized fibrosis is a sequela of healing.
SUBMITTER: Perkins JA
PROVIDER: S-EPMC2562732 | biostudies-literature | 2008 Aug
REPOSITORIES: biostudies-literature
Publications
Morphologic and histologic outcomes of tongue reduction surgery in an animal model.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20080801 2
<h4>Objective</h4>To describe the effect of anterior tongue reduction surgery on tongue size, morphology, and histology.<h4>Design</h4>Prospective experiment.<h4>Materials</h4>Twenty-two 12-week-old Yucatan minipigs.<h4>Methods</h4>Six sibling pairs had tongue reduction (Group B) or sham surgery (Group A), and underwent euthanasia the day of surgery. Five sibling pairs had tongue reduction (Group D) or sham surgery (Group C), and were raised for four weeks. Data collected included changes in ton ...[more]
