Palladium asymmetric allylic alkylation of prochiral nucleophiles: horsfiline.

ABSTRACT: [reaction; see text] The asymmetric synthesis of the oxindole alkaloid horsfiline is described. A palladium-catalyzed asymmetric allylic alkylation (AAA) is used to set the spiro(pyrrolidine-oxindole) stereogenic center.

SUBMITTER: Trost BM 

PROVIDER: S-EPMC2565574 | biostudies-literature | 2006 May

REPOSITORIES: biostudies-literature