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Nanoscale magnetic resonance imaging.

ABSTRACT: We have combined ultrasensitive magnetic resonance force microscopy (MRFM) with 3D image reconstruction to achieve magnetic resonance imaging (MRI) with resolution <10 nm. The image reconstruction converts measured magnetic force data into a 3D map of nuclear spin density, taking advantage of the unique characteristics of the "resonant slice" that is projected outward from a nanoscale magnetic tip. The basic principles are demonstrated by imaging the (1)H spin density within individual tobacco mosaic virus particles sitting on a nanometer-thick layer of adsorbed hydrocarbons. This result, which represents a 100 million-fold improvement in volume resolution over conventional MRI, demonstrates the potential of MRFM as a tool for 3D, elementally selective imaging on the nanometer scale.

SUBMITTER: Degen CL

PROVIDER: S-EPMC2628306 | biostudies-literature | 2009 Feb

REPOSITORIES: biostudies-literature

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Nanoscale magnetic resonance imaging.

Degen C L CL Poggio M M Mamin H J HJ Rettner C T CT Rugar D D

Proceedings of the National Academy of Sciences of the United States of America 20090112 5

We have combined ultrasensitive magnetic resonance force microscopy (MRFM) with 3D image reconstruction to achieve magnetic resonance imaging (MRI) with resolution <10 nm. The image reconstruction converts measured magnetic force data into a 3D map of nuclear spin density, taking advantage of the unique characteristics of the "resonant slice" that is projected outward from a nanoscale magnetic tip. The basic principles are demonstrated by imaging the (1)H spin density within individual tobacco m ...[more]

PMID: 19139397

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