Ontology highlight
ABSTRACT:
SUBMITTER: Seward GK
PROVIDER: S-EPMC2645951 | biostudies-literature | 2008 Nov
REPOSITORIES: biostudies-literature
Seward Garry K GK Wei Qian Q Dmochowski Ivan J IJ
Bioconjugate chemistry 20081101 11
Cryptophane-A has generated considerable interest based on its high affinity for xenon and potential for creating biosensors for (129)Xe nuclear magnetic resonance (NMR) spectroscopy. Here, we report the cellular delivery of three peptide-functionalized cryptophane biosensors. Cryptophanes were delivered using two cationic cell penetrating peptides into several human cancer and normal cell lines. An RGD peptide targeting alpha(v)beta(3) integrin receptor was shown to increase specificity of cryp ...[more]