Oxygen-directed intramolecular hydroboration.

ABSTRACT: Metal-free homoallylic oxygen-directed intramolecular hydroboration is reported. Regioselectivities from 20:1 to 82:1 favoring the 1,3-dioxy-substituted products have been achieved using Me2S.BH3/TfOH followed by standard oxidative workup. Branching at the C5 position improves regioselectivity.

SUBMITTER: Rarig RA 

PROVIDER: S-EPMC2646882 | biostudies-literature | 2008 Jul

REPOSITORIES: biostudies-literature