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FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions.

ABSTRACT: EdgeExpressDB is a novel database and set of interfaces for interpreting biological networks and comparing large high-throughput expression datasets that requires minimal development for new data types and search patterns. The FANTOM4 EdgeExpress database http://fantom.gsc.riken.jp/4/edgeexpress summarizes gene expression patterns in the context of alternative promoter structures and regulatory transcription factors and microRNAs using intuitive gene-centric and sub-network views. This is an important resource for gene regulation in acute myeloid leukemia, monocyte/macrophage differentiation and human transcriptional networks.

SUBMITTER: Severin J

PROVIDER: S-EPMC2688930 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature

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FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions.

Severin Jessica J Waterhouse Andrew M AM Kawaji Hideya H Lassmann Timo T van Nimwegen Erik E Balwierz Piotr J PJ de Hoon Michiel Jl MJ Hume David A DA Carninci Piero P Hayashizaki Yoshihide Y Suzuki Harukazu H Daub Carsten O CO Forrest Alistair Rr AR

Genome biology 20090419 4

EdgeExpressDB is a novel database and set of interfaces for interpreting biological networks and comparing large high-throughput expression datasets that requires minimal development for new data types and search patterns. The FANTOM4 EdgeExpress database http://fantom.gsc.riken.jp/4/edgeexpress summarizes gene expression patterns in the context of alternative promoter structures and regulatory transcription factors and microRNAs using intuitive gene-centric and sub-network views. This is an imp ...[more]

PMID: 19374773

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