Risk factors for neurocognitive dysfunction after cardiac surgery in postmenopausal women.

ABSTRACT:

Background

Women are at higher risk than men for neurologic complications from cardiac operations. This study identified risk factors for neurocognitive dysfunction after cardiac operations in elderly women.

Methods

One hundred thirteen postmenopausal women undergoing primary coronary artery bypass grafting, with or without valve operation, underwent psychometric testing and neurologic evaluation the day before operation and 4 to 6 weeks postoperatively. Risk factors assessed for neurologic complications included atherosclerosis of the ascending aorta and apolipoprotein epsilon4 genotype. Postoperative neurocognitive dysfunction was defined as the composite end point of a one standard deviation decrement from baseline on two or more psychometric tests or a new neurologic def

SUBMITTER: Hogue CW 

PROVIDER: S-EPMC2784735 | biostudies-literature | 2008 Aug

REPOSITORIES: biostudies-literature