Impact of smoking on patients with stage III colon cancer: results from Cancer and Leukemia Group B 89803.

ABSTRACT:

Background

Cigarette smoking has been shown to increase the risk of developing colorectal cancer, particularly smoking early in life. Little is known about the impact of tobacco use on colon cancer recurrence among colon cancer survivors.

Methods

The authors prospectively collected lifetime smoking history from stage III colon cancer patients enrolled in a phase 3 trial via self-report questionnaires during and 6 months after completion of adjuvant chemotherapy. Smoking status was defined as never, current, or past. Lifetime pack-years were defined as number of lifetime packs of cigarettes. Patients were followed for recurrence or death.

Results

Data on smoking history were captured on 1045 patients with stage III colon cancer receiving adjuvant therapy (46% never smo

SUBMITTER: McCleary NJ 

PROVIDER: S-EPMC2884300 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature