Ontology highlight
ABSTRACT:
SUBMITTER: Ingelmo-Torres M
PROVIDER: S-EPMC2913680 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Ingelmo-Torres Mercedes M González-Moreno Elena E Kassan Adam A Hanzal-Bayer Michael M Tebar Francesc F Herms Albert A Grewal Thomas T Hancock John F JF Enrich Carlos C Bosch Marta M Gross Steven P SP Parton Robert G RG Pol Albert A
Traffic (Copenhagen, Denmark) 20091005 12
In recent years, progress in the study of the lateral organization of the plasma membrane has led to the proposal that mammalian cells use two different organelles to store lipids: intracellular lipid droplets (LDs) and plasma membrane caveolae. Experimental evidence suggests that caveolin (CAV) may act as a sensitive lipid-organizing molecule that physically connects these two lipid-storing organelles. Here, we determine the sequences necessary for efficient sorting of CAV to LDs. We show that ...[more]