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Physiologic upper limits of pore size of different blood capillary types and another perspective on the dual pore theory of microvascular permeability.


ABSTRACT:

SUBMITTER: Sarin H 

PROVIDER: S-EPMC2928191 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature

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Physiologic upper limits of pore size of different blood capillary types and another perspective on the dual pore theory of microvascular permeability.

Sarin Hemant H  

Journal of angiogenesis research 20100811


<h4>Background</h4>Much of our current understanding of microvascular permeability is based on the findings of classic experimental studies of blood capillary permeability to various-sized lipid-insoluble endogenous and non-endogenous macromolecules. According to the classic small pore theory of microvascular permeability, which was formulated on the basis of the findings of studies on the transcapillary flow rates of various-sized systemically or regionally perfused endogenous macromolecules, t  ...[more]