Prevalence of alternative splicing choices in Arabidopsis thaliana.

ABSTRACT:

Background

Around 14% of protein-coding genes of Arabidopsis thaliana genes from the TAIR9 genome release are annotated as producing multiple transcript variants through alternative splicing. However, for most alternatively spliced genes in Arabidopsis, the relative expression level of individual splicing variants is unknown.

Results

We investigated prevalence of alternative splicing (AS) events in Arabidopsis thaliana using ESTs. We found that for most AS events with ample EST coverage, the majority of overlapping ESTs strongly supported one major splicing choice, with less than 10% of ESTs supporting the minor form. Analysis of ESTs also revealed a small but noteworthy subset of genes for which alternative choices appeared with about equal prevalence, suggesting that for t

SUBMITTER: English AC 

PROVIDER: S-EPMC3017808 | biostudies-literature | 2010 Jun

REPOSITORIES: biostudies-literature