Ontology highlight
ABSTRACT:
SUBMITTER: Choi SM
PROVIDER: S-EPMC3158714 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Blood 20110531 7
EBV-immortalized B lymphocyte cell lines have been widely banked for studying a variety of diseases, including rare genetic disorders. These cell lines represent an important resource for disease modeling with the induced pluripotent stem cell (iPSC) technology. Here we report the generation of iPSCs from EBV-immortalized B-cell lines derived from multiple inherited disease patients via a nonviral method. The reprogramming method for the EBV cell lines involves a distinct protocol compared with ...[more]