Ontology highlight
ABSTRACT:
SUBMITTER: Kirk PD
PROVIDER: S-EPMC3210102 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Kirk Paul D W PD Witkover Aviva A Courtney Alan A Lewin Alexandra M AM Wait Robin R Stumpf Michael P H MP Richardson Sylvia S Taylor Graham P GP Bangham Charles R M CR
Retrovirology 20111012
<h4>Background</h4>Human T lymphotropic virus Type 1 (HTLV-1) causes a chronic inflammatory disease of the central nervous system known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM) which resembles chronic spinal forms of multiple sclerosis (MS). The pathogenesis of HAM remains uncertain. To aid in the differential diagnosis of HAM and to identify pathogenetic mechanisms, we analysed the plasma proteome in asymptomatic HTLV-1 carriers (ACs), patients with HAM, uninfected con ...[more]