Prognostic factors in chemotherapy-treated patients with HIV-associated Plasmablastic lymphoma.

ABSTRACT:

Background

Plasmablastic lymphoma (PBL) is a variant of diffuse large B-cell lymphoma commonly seen in the oral cavity of HIV-infected individuals. PBL has a poor prognosis, but prognostic factors in patients who have received chemotherapy have not been adequately evaluated.

Methods

An extensive literature search rendered 248 cases of PBL, from which 157 were HIV(+). Seventy cases with HIV-associated PBL that received chemotherapy were identified. Whenever possible, authors of the original reports were contacted to complete clinicopathological data. Univariate analyses were performed calculating Kaplan-Meier estimates and compared using the log-rank test.

Results

The mean age was 39 years, with a male predominance. The mean CD4(+) count was 165 cells/mm(3). Advanced c

SUBMITTER: Castillo JJ 

PROVIDER: S-EPMC3227958 | biostudies-literature | 2010

REPOSITORIES: biostudies-literature