Genome of halomonas strain GFAJ-1, a blueprint for fame or business as usual.
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ABSTRACT:
SUBMITTER: Kim EH
PROVIDER: S-EPMC3302460 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Publications
Genome of halomonas strain GFAJ-1, a blueprint for fame or business as usual.
Kim Eun-Hae EH Rensing Christopher C
Journal of bacteriology 20120120 7
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Project description:Halomonas strain GFAJ-1 was reported in Science magazine to be a remarkable microbe for which there was "arsenate in macromolecules that normally contain phosphate, most notably nucleic acids." The draft genome of the bacterium was determined (NCBI accession numbers AHBC01000001 through AHBC01000103). It appears to be a typical gamma proteobacterium.
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Project description:BackgroundAntimicrobial Stewardship (AMS), the set of actions to ensure appropriate antimicrobial use, is increasingly considered a multidisciplinary endeavour. However, it is unclear how Dutch hospital-based nurses envision their contribution to AMS.ObjectiveTo explore the views and visions of Dutch bedside nurses on their role regarding appropriate antimicrobial use.MethodsA qualitative study using semi-structured interviews was conducted. Fourteen bedside nurses in nine different Dutch hospitals participated. Data were analysed using a thematic content analysis.ResultsNurses considered their role regarding appropriate use of antibiotics as an integral part of their daily nursing practice. They envisioned their future role as an expansion of their current practice, improving or intensifying this contribution. Prompting review of antimicrobial treatment by nurses was seen as regular practice. Ward rounds were considered the best moment to exert their nursing role, by showing leadership in communicating about different aspects of AMS. Patient advocacy ("striving for the best possible care for their patient") appears to be a driver of the nursing contribution. Nurses perceived a shared responsibility with prescribers on certain aspects of the antimicrobial treatment and wished for a clarification of this role. Education and cognitive reminders such as antibiotic checklist to be used in ward rounds, can support the uptake of the nurses' role.ConclusionNurses envision their future role in AMS as an enhanced, elaborated and empowered version of their current daily practice. Education, formal acknowledgment and increased awareness of the nursing role, may advance the contributing role nurses already have.
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