Crystal structure and silica condensing activities of silicatein alpha-cathepsin L chimeras.
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ABSTRACT:
SUBMITTER: Fairhead M
PROVIDER: S-EPMC3326524 | biostudies-literature | 2008 Apr
REPOSITORIES: biostudies-literature
Publications
Crystal structure and silica condensing activities of silicatein alpha-cathepsin L chimeras.
Fairhead Michael M Johnson Kenneth A KA Kowatz Thomas T McMahon Stephen A SA Carter Lester G LG Oke Muse M Liu Huanting H Naismith James H JH van der Walle Christopher F CF
Chemical communications (Cambridge, England) 20080211 15
Cathepsin L mutants with the ability to condense silica from solution have been generated and a 1.5 A crystal structure of one of these chimeras allows us to rationalise the catalytic mechanism of silicic acid condensation. ...[more]
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