Unravelling global genome organization by 3C-seq.
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ABSTRACT:
SUBMITTER: Tanizawa H
PROVIDER: S-EPMC3362197 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Publications
Unravelling global genome organization by 3C-seq.
Tanizawa Hideki H Noma Ken-ichi K
Seminars in cell & developmental biology 20111118 2
Eukaryotic genomes exist in the cell nucleus as an elaborate three-dimensional structure which reflects various nuclear processes such as transcription, DNA replication and repair. Next-generation sequencing (NGS) combined with chromosome conformation capture (3C), referred to as 3C-seq in this article, has recently been applied to the yeast and human genomes, revealing genome-wide views of functional associations among genes and their regulatory elements. Here, we compare the latest genomic app ...[more]
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