Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective study.

ABSTRACT:

Background

Coffee and tea are widely consumed globally and are rich sources of potential chemopreventive compounds. Epidemiologic data for coffee and tea intakes in relation to colorectal cancer remain unclear. Despite differences in gut physiology, few studies have conducted investigations by anatomic subsites.

Objective

We evaluated coffee and tea intakes (caffeinated and decaffeinated) in relation to colon (proximal and distal) and rectal cancers.

Design

The NIH-AARP Diet and Health Study included 489,706 men and women who completed a baseline (1995-1996) self-administered questionnaire of demographics, diet, and lifestyle. Over a median of 10.5 y of follow-up, we identified 2863 proximal colon, 1993 distal colon, and 1874 rectal cancers. Multivariable HRs and 95%

SUBMITTER: Sinha R 

PROVIDER: S-EPMC3396445 | biostudies-literature | 2012 Aug

REPOSITORIES: biostudies-literature