Serum PBDEs in a North Carolina toddler cohort: associations with handwipes, house dust, and socioeconomic variables.

ABSTRACT:

Background

Polybrominated diphenyl ethers (PBDEs) are persistent, bioaccumulative, and endocrine-disrupting chemicals.

Objectives

We used handwipes to estimate exposure to PBDEs in house dust among toddlers and examined sex, age, breast-feeding, race, and parents' education as predictors of serum PBDEs.

Methods

Eighty-three children from 12 to 36 months of age were enrolled in North Carolina between May 2009 and November 2010. Blood, handwipe, and house dust samples were collected and analyzed for PBDEs. A questionnaire was administered to collect demographic data.

Results

PBDEs were detected in all serum samples (geometric mean for ΣpentaBDE in serum was 43.3 ng/g lipid), 98% of the handwipe samples, and 100% of the dust samples. Serum ΣpentaBDEs were signific

SUBMITTER: Stapleton HM 

PROVIDER: S-EPMC3404669 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature