Reduced osmolarity oral rehydration solution for treating dehydration due to diarrhoea in children: systematic review.

ABSTRACT:

Objectives

To compare reduced osmolarity oral rehydration solution with standard World Health Organization oral rehydration solution in children with acute diarrhoea.

Design

Systematic review of randomised controlled trials.

Studies

15 randomised controlled trials including 2397 randomised patients.

Outcomes

The primary outcome was unscheduled intravenous infusion; secondary outcomes were stool output, vomiting, and hyponatraemia.

Results

In a meta-analysis of nine trials for the primary outcome, reduced osmolarity rehydration solution was associated with fewer unscheduled intravenous infusions compared with standard WHO rehydration solution (odds ratio 0.61, 95% confidence interval 0.47 to 0.81). Three trials reported that no patients required unschedul

SUBMITTER: Hahn S 

PROVIDER: S-EPMC34542 | biostudies-literature | 2001 Jul

REPOSITORIES: biostudies-literature