Ontology highlight
ABSTRACT:
SUBMITTER: International Stem Cell Initiative
PROVIDER: S-EPMC3454460 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Nature biotechnology 20111127 12
The International Stem Cell Initiative analyzed 125 human embryonic stem (ES) cell lines and 11 induced pluripotent stem (iPS) cell lines, from 38 laboratories worldwide, for genetic changes occurring during culture. Most lines were analyzed at an early and late passage. Single-nucleotide polymorphism (SNP) analysis revealed that they included representatives of most major ethnic groups. Most lines remained karyotypically normal, but there was a progressive tendency to acquire changes on prolong ...[more]