Role of long- and short-range hydrophobic, hydrophilic and charged residues contact network in protein's structural organization.
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ABSTRACT:
SUBMITTER: Sengupta D
PROVIDER: S-EPMC3464617 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Publications
Role of long- and short-range hydrophobic, hydrophilic and charged residues contact network in protein's structural organization.
Sengupta Dhriti D Kundu Sudip S
BMC bioinformatics 20120621
<h4>Background</h4>The three-dimensional structure of a protein can be described as a graph where nodes represent residues and the strength of non-covalent interactions between them are edges. These protein contact networks can be separated into long and short-range interactions networks depending on the positions of amino acids in primary structure. Long-range interactions play a distinct role in determining the tertiary structure of a protein while short-range interactions could largely contri ...[more]
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