Epistasis analysis for estrogen metabolic and signaling pathway genes on young ischemic stroke patients.

ABSTRACT:

Background

Endogenous estrogens play an important role in the overall cardiocirculatory system. However, there are no studies exploring the hormone metabolism and signaling pathway genes together on ischemic stroke, including sulfotransferase family 1E (SULT1E1), catechol-O-methyl-transferase (COMT), and estrogen receptor α (ESR1).

Methods

A case-control study was conducted on 305 young ischemic stroke subjects aged

SUBMITTER: Hsieh YC 

PROVIDER: S-EPMC3480403 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature