Troponin T, B-type natriuretic peptide, C-reactive protein, and cause-specific mortality.

ABSTRACT:

Purpose

We sought to evaluate the associations of high-sensitivity troponin T (Hs-TnT), N-terminal pro-brain natriuretic peptide (NT-proBNP), and high sensitivity C-reactive protein (Hs-CRP) with mortality from any cause, cardiovascular disease (CVD), coronary heart disease (CHD), stroke, cancer, and respiratory disease in the Atherosclerosis Risk in Communities cohort.

Methods

We included 11,193 participants aged 54 to 74 years, initially free of the conditions being studied, and who had biomarkers measured. Participants were followed for a mean of 9.9 years.

Results

Hazard ratios (HR), adjusted for multiple risk factors, for mortality in participants in the highest Hs-TnT category compared with those with undetectable levels were: Total 3.42 (95% confidence interval

SUBMITTER: Oluleye OW 

PROVIDER: S-EPMC3543509 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature