Potential quantitative magnetic resonance imaging biomarkers of coronary remodeling in older hypertensive patients.

ABSTRACT:

Objective

To detect differences in potential magnetic resonance imaging biomarkers of coronary remodeling between older hypertensive patients and healthy controls.

Methods and results

Two-dimensional black-blood coronary wall magnetic resonance imaging and 3-dimensional whole-heart coronary magnetic resonance angiography were performed on 130 participants (65-84 years), including 65 hypertensive patients and 65 healthy controls. Coronary segments derived from hypertensive participants had a higher mean coronary wall thickness, a smaller vessel area, a smaller coronary wall area, a smaller lumen area, a lower coronary distensibility index, and a higher percent of the coronary wall occupying the vessel area (PWOV) than those from healthy controls. When the average PWOV was set

SUBMITTER: Lin K 

PROVIDER: S-EPMC3558937 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature