Response to CPAP withdrawal in patients with mild versus severe obstructive sleep apnea/hypopnea syndrome.

ABSTRACT:

Background

Patients with obstructive sleep apnea/hypopnea syndrome (OSAHS), even those generally compliant with CPAP therapy, often intermittently discontinue CPAP.

Study objective

Examine the impact of CPAP withdrawal on sleep, sleep disordered breathing (SDB), and daytime function in subjects with varying severity of OSAHS.

Patients and interventions

Forty-two subjects (26M/16 F) with OSAHS (AHI4% = 45.2 ± 35.5/h pretreatment) on CPAP for 4 months were evaluated on the second night of CPAP withdrawal. Sleep architecture, SDB indices, and subjective/objective daytime function were assessed pretreatment, on CPAP therapy, and after CPAP withdrawal. Comparisons were made between pretreatment and CPAP withdrawal for the entire group, and for subgroups of mild/moderate (A

SUBMITTER: Young LR 

PROVIDER: S-EPMC3571747 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature