Patients with celiac disease and B-cell lymphoma have a better prognosis than those with T-cell lymphoma.

ABSTRACT:

Background & aims

Celiac disease (CD) is associated with an increased risk of lymphoma. However, relatively few studies have assessed the outcome of patients diagnosed with both CD and lymphoma. We evaluated the temporal association between lymphoma and CD, along with clinical presentation, response to therapy, and prognosis.

Methods

Patients diagnosed with both CD and lymphoma were identified retrospectively in a tertiary referral center. Clinical characteristics and survival were analyzed.

Results

Sixty-three patients (36 men) were identified who had been diagnosed with lymphoma and CD. Thirty-six (57%) were diagnosed with CD before they were diagnosed with lymphoma. The most common histologic entity was diffuse, large, B-cell lymphoma, which affected 18 (29%) patie

SUBMITTER: Halfdanarson TR 

PROVIDER: S-EPMC3594736 | biostudies-literature | 2010 Dec

REPOSITORIES: biostudies-literature