Default mode network connectivity distinguishes chemotherapy-treated breast cancer survivors from controls.
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ABSTRACT:
SUBMITTER: Kesler SR
PROVIDER: S-EPMC3710809 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Publications
Default mode network connectivity distinguishes chemotherapy-treated breast cancer survivors from controls.
Kesler Shelli R SR Wefel Jeffrey S JS Hosseini S M Hadi SM Cheung Maria M Watson Christa L CL Hoeft Fumiko F
Proceedings of the National Academy of Sciences of the United States of America 20130624 28
Breast cancer (BC) chemotherapy is associated with cognitive changes including persistent deficits in some individuals. We tested the accuracy of default mode network (DMN) resting state functional connectivity patterns in discriminating chemotherapy treated (C+) from non-chemotherapy (C-) treated BC survivors and healthy controls (HC). We also examined the relationship between DMN connectivity patterns and cognitive function. Multivariate pattern analysis was used to classify 30 C+, 27 C-, and ...[more]
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