Single nucleotide polymorphisms and haplotypes associated with feed efficiency in beef cattle.

ABSTRACT:

Background

General, breed- and diet-dependent associations between feed efficiency in beef cattle and single nucleotide polymorphisms (SNPs) or haplotypes were identified on a population of 1321 steers using a 50 K SNP panel. Genomic associations with traditional two-step indicators of feed efficiency - residual feed intake (RFI), residual average daily gain (RADG), and residual intake gain (RIG) - were compared to associations with two complementary one-step indicators of feed efficiency: efficiency of intake (EI) and efficiency of gain (EG). Associations uncovered in a training data set were evaluated on independent validation data set. A multi-SNP model was developed to predict feed efficiency. Functional analysis of genes harboring SNPs significantly associated with feed effici

SUBMITTER: Serao NV 

PROVIDER: S-EPMC3819741 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature