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Statin use is not associated with reduced risk of skin cancer: a meta-analysis.


ABSTRACT:

Background

There is contradictory evidence about the association between statin and skin cancer.

Methods

Literature search in PubMed and Web of Science was undertaken up to June 2013. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated.

Result

A total of 21 articles with 29 studies were identified. No association was found between statin and skin cancer among neither melanoma (RR, 0.94; 95% CI, 0.85-1.04) nor non-melanoma skin cancer (RR, 1.03; 95% CI, 0.90-1.19).

Conclusion

Our meta-analysis does not support a potential role of statin use in the prevention of skin cancer.

SUBMITTER: Li X 

PROVIDER: S-EPMC3915126 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature

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Publications

Statin use is not associated with reduced risk of skin cancer: a meta-analysis.

Li X X   Wu X B XB   Chen Q Q  

British journal of cancer 20131224 3


<h4>Background</h4>There is contradictory evidence about the association between statin and skin cancer.<h4>Methods</h4>Literature search in PubMed and Web of Science was undertaken up to June 2013. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated.<h4>Result</h4>A total of 21 articles with 29 studies were identified. No association was found between statin and skin cancer among neither melanoma (RR, 0.94; 95% CI, 0.85-1.04) nor non-melanoma skin cancer (RR,  ...[more]

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