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ABSTRACT: Introduction
The aim of this study was to test the proficiency (accuracy among evaluators) of measured attributes of nerve conduction (NC).Methods
Expert clinical neurophysiologists, without instruction or consensus development, from 4 different medical centers, independently assessed 8 attributes of NC in 24 patients with diabetes mellitus (DM) on consecutive days.Results
No significant intraobserver differences between days 1 and 2 were found, but significant interobserver differences were seen. Use of standard reference values did not correct for these observed differences.Conclusions
Interobserver variability was attributed to differences in performance of NC. It was of sufficient magnitude that it is of concern for the conduct of therapeutic trials. To deal with interrater variability in therapeutic trials, the same electromyographers should perform all NC assessments of individual patients or, preferably, NC procedures should be more standardized. A further trial is needed to test whether such standardization would eliminate interobserver variability.
SUBMITTER: Dyck PJ
PROVIDER: S-EPMC3966293 | biostudies-literature | 2013 Sep
REPOSITORIES: biostudies-literature
Dyck Peter J PJ Albers James W JW Wolfe James J Bolton Charles F CF Walsh Nancy N Klein Christopher J CJ Zafft Andrew J AJ Russell James W JW Thomas Karen K Davies Jenny L JL Carter Rickey E RE Melton L Joseph LJ Litchy William J WJ
Muscle & nerve 20130717 3
<h4>Introduction</h4>The aim of this study was to test the proficiency (accuracy among evaluators) of measured attributes of nerve conduction (NC).<h4>Methods</h4>Expert clinical neurophysiologists, without instruction or consensus development, from 4 different medical centers, independently assessed 8 attributes of NC in 24 patients with diabetes mellitus (DM) on consecutive days.<h4>Results</h4>No significant intraobserver differences between days 1 and 2 were found, but significant interobser ...[more]