Metabolomic patterns and alcohol consumption in African Americans in the Atherosclerosis Risk in Communities Study.

ABSTRACT:

Background

Effects of alcohol consumption on health and disease are complex and involve a number of cellular and metabolic processes.

Objective

We examined the association between alcohol consumption habits and metabolomic profiles.

Design

We conducted a cross-sectional study to explore the association of alcohol consumption habits measured by using a questionnaire with serum metabolites measured by using untargeted mass spectrometry in 1977 African Americans from the Jackson field center in the Atherosclerosis Risk in Communities Study. The whole sample was split into a discovery set (n = 1500) and a replication set (n = 477). Alcohol consumption habits were treated as an ordinal variable, with nondrinkers as the reference group and quartiles of current drinkers as o

SUBMITTER: Zheng Y 

PROVIDER: S-EPMC4021786 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature