Ontology highlight
ABSTRACT:
SUBMITTER: Miyajima S
PROVIDER: S-EPMC4044620 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Scientific reports 20140604
A relationship between periodontal disease and atherosclerosis has been suggested by epidemiological studies. Ligature-induced experimental periodontitis is an adequate model for clinical periodontitis, which starts from plaque accumulation, followed by inflammation in the periodontal tissue. Here we have demonstrated using a ligature-induced periodontitis model that periodontitis activates monocytes/macrophages, which subsequently circulate in the blood and adhere to vascular endothelial cells ...[more]