Erratum: Differential expressed genes in ECV304 Endothelial-like Cells infected with Human Cytomegalovirus.

ABSTRACT:

Background

Human cytomegalovirus (HCMV) is a virus which has the potential to alter cellular gene expression through multiple mechanisms.

Objective

With the application of DNA microarrays, we could monitor the effects of pathogens on host-cell gene expression programmes in great depth and on a broad scale.

Methods

Changes in mRNA expression levels of human endothelial-like ECV304 cells following infection with human cytomegalovirus AD169 strain was analyzed by a microarray system comprising 21073 60-mer oligonucleotide probes which represent 18716 human genes or transcripts.

Results

The results from cDNA microarray showed that there were 559 differential expressed genes consisted of 471 upregulated genes and 88 down-regulated genes. Real-time qPCR was performed

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC4056481 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature