Ontology highlight
ABSTRACT:
SUBMITTER: Divito CB
PROVIDER: S-EPMC4058416 | biostudies-literature | 2014 Jul
REPOSITORIES: biostudies-literature
Divito Christopher B CB Underhill Suzanne M SM
Neurochemistry international 20140110
Excitatory amino acid transporters or EAATs are the major transport mechanism for extracellular glutamate in the nervous system. This family of five carriers not only displays an impressive ability to regulate ambient extracellular glu concentrations but also regulate the temporal and spatial profile of glu after vesicular release. This dynamic form of regulation mediates several characteristic of synaptic, perisynaptic, and spillover activation of ionotropic and metabotropic receptors. EAATs fu ...[more]