Evaluating the contribution of the cause of kidney disease to prognosis in CKD: results from the Study of Heart and Renal Protection (SHARP).

ABSTRACT:

Background

The relevance of the cause of kidney disease to prognosis among patients with chronic kidney disease is uncertain.

Study design

Observational study.

Settings & participants

6,245 nondialysis participants in the Study of Heart and Renal Protection (SHARP).

Predictor

Baseline cause of kidney disease was categorized into 4 groups: cystic kidney disease, diabetic nephropathy, glomerulonephritis, and other recorded diagnoses.

Outcomes

End-stage renal disease (ESRD; dialysis or transplantation) and death.

Results

During an average 4.7 years' follow-up, 2,080 participants progressed to ESRD, including 454 with cystic kidney disease (23% per year), 378 with glomerulonephritis (10% per year), 309 with diabetic nephropathy (12% per year), and 939

SUBMITTER: Haynes R 

PROVIDER: S-EPMC4068325 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature