Medial vascular calcification revisited: review and perspectives.
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ABSTRACT:
SUBMITTER: Lanzer P
PROVIDER: S-EPMC4072893 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Publications
Medial vascular calcification revisited: review and perspectives.
Lanzer Peter P Boehm Manfred M Sorribas Victor V Thiriet Marc M Janzen Jan J Zeller Thomas T St Hilaire Cynthia C Shanahan Catherine C
European heart journal 20140416 23
Vascular calcifications (VCs) are actively regulated biological processes associated with crystallization of hydroxyapatite in the extracellular matrix and in cells of the media (VCm) or intima (VCi) of the arterial wall. Both patterns of VC often coincide and occur in patients with type II diabetes, chronic kidney disease, and other less frequent disorders; VCs are also typical in senile degeneration. In this article, we review the current state of knowledge about the pathology, molecular biolo ...[more]
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