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Optimizing the selective recognition of protein isoforms through tuning of nanoparticle hydrophobicity.


ABSTRACT: We demonstrate that ligand hydrophobicity can be used to increase affinity and selectivity of binding between monolayer-protected cationic gold nanoparticles and β-lactoglobulin protein isoforms containing two amino acid mutations.

SUBMITTER: Chen K 

PROVIDER: S-EPMC4073475 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature