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Biological consequences of zinc deficiency in the pathomechanisms of selected diseases.


ABSTRACT: From many points of view, zinc is one of the most important trace elements in biological systems. Many articles describe the well-known role of this metal in human physiology and pathophysiology, but in the related literature, there is a lack of current and reliable reviews of the role of zinc deficiency in many diseases. In this article, we describe the role of zinc deficiency in the oxidative stress control, immune response, proliferation, and pathogenesis and pathophysiology of selected diseases such as depression, cardiovascular diseases, diabetes mellitus, Alzheimer's disease, and Wilson's disease.

SUBMITTER: Jurowski K 

PROVIDER: S-EPMC4175048 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature

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Biological consequences of zinc deficiency in the pathomechanisms of selected diseases.

Jurowski Kamil K   Szewczyk Bernadeta B   Nowak Gabriel G   Piekoszewski Wojciech W  

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20140419 7


From many points of view, zinc is one of the most important trace elements in biological systems. Many articles describe the well-known role of this metal in human physiology and pathophysiology, but in the related literature, there is a lack of current and reliable reviews of the role of zinc deficiency in many diseases. In this article, we describe the role of zinc deficiency in the oxidative stress control, immune response, proliferation, and pathogenesis and pathophysiology of selected disea  ...[more]

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