Tumor surveillance by circulating microRNAs: a hypothesis.
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ABSTRACT:
SUBMITTER: Igaz I
PROVIDER: S-EPMC4194016 | biostudies-literature | 2014 Nov
REPOSITORIES: biostudies-literature
Publications
Tumor surveillance by circulating microRNAs: a hypothesis.
Cellular and molecular life sciences : CMLS 20140719 21
A growing body of experimental evidence supports the diagnostic relevance of circulating microRNAs in various diseases including cancer. The biological relevance of circulating microRNAs is, however, largely unknown, particularly in healthy individuals. Here, we propose a hypothesis based on the relative abundance of microRNAs with predominant tumor suppressor activity in the blood of healthy individuals. According to our hypothesis, certain sets of circulating microRNAs might function as a tumo ...[more]
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