Dataset Information

Low-to-moderate prenatal alcohol consumption and the risk of selected birth outcomes: a prospective cohort study.

ABSTRACT:

Purpose

To estimate whether low-to-moderate prenatal alcohol exposure is associated with selected birth outcomes.

Methods

Low-to-moderate prenatal alcohol drinking and effects on low birthweight, preterm delivery, intrauterine growth restriction, and selected neonatal outcomes were evaluated among 4496 women and singleton infants. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariable logistic regression, controlling for confounding variables.

Results

Early pregnancy drinking was associated with reduced odds of low birthweight, OR, 0.66 (95% CI, 0.46-0.96) and birth length less than 10th percentile, OR, 0.74 (95% CI, 0.56-0.97). Drinking during the first 3 months showed lower odds for birth length and head circumference less than 10th percentile, OR, 0.56 (95% CI, 0.36-0.87) and OR, 0.69 (95% CI, 0.50-0.96), respectively. Third trimester drinking was associated with lower odds for low birthweight, OR, 0.56 (95% CI, 0.34-0.94) and preterm delivery, OR, 0.60 (95% CI, 0.42-0.87).

Conclusions

Our results suggest low-to-moderate alcohol exposure during early and late gestation is not associated with increased risk of low birthweight, preterm delivery, intrauterine growth restriction, and most selected perinatal outcomes.

SUBMITTER: Lundsberg LS

PROVIDER: S-EPMC4255148 | biostudies-literature | 2015 Jan

REPOSITORIES: biostudies-literature

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Publications

Low-to-moderate prenatal alcohol consumption and the risk of selected birth outcomes: a prospective cohort study.

Lundsberg Lisbet S LS Illuzzi Jessica L JL Belanger Kathleen K Triche Elizabeth W EW Bracken Michael B MB

Annals of epidemiology 20141016 1

<h4>Purpose</h4>To estimate whether low-to-moderate prenatal alcohol exposure is associated with selected birth outcomes.<h4>Methods</h4>Low-to-moderate prenatal alcohol drinking and effects on low birthweight, preterm delivery, intrauterine growth restriction, and selected neonatal outcomes were evaluated among 4496 women and singleton infants. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using multivariable logistic regression, controlling for confounding variables.<h4> ...[more]

PMID: 25453352

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Dataset Information

Low-to-moderate prenatal alcohol consumption and the risk of selected birth outcomes: a prospective cohort study.

Purpose

Methods

Results

Conclusions

Publications

Low-to-moderate prenatal alcohol consumption and the risk of selected birth outcomes: a prospective cohort study.

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