Promoting Precision Cancer Medicine through a Community-Driven Knowledgebase.

ABSTRACT: Increasing efforts are being dedicated towards improving cancer care via personalized medicine. These efforts depend to a large degree on the availability of a knowledge foundation. Unfortunately, existing knowledge linking cancer drugs and potential efficacy biomarkers is in its infancy; and where links are known, they are frequently unstructured and poorly documented. We have developed a new open-access knowledgebase for precision cancer medicine (the PCM Wiki and Knowledgebase). This knowledgebase was constructed using an innovative, two-pronged approach involving a structured knowledgebase at the back-end, and an intuitive knowledge-sharing interface and user-friendly query engine in front. The knowledgebase was seeded with several patient case reports and information was mined via tex

SUBMITTER: Geifman N 

PROVIDER: S-EPMC4282884 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature