An organ boundary-enriched gene regulatory network uncovers regulatory hierarchies underlying axillary meristem initiation.

ABSTRACT: Gene regulatory networks (GRNs) control development via cell type-specific gene expression and interactions between transcription factors (TFs) and regulatory promoter regions. Plant organ boundaries separate lateral organs from the apical meristem and harbor axillary meristems (AMs). AMs, as stem cell niches, make the shoot a ramifying system. Although AMs have important functions in plant development, our knowledge of organ boundary and AM formation remains rudimentary. Here, we generated a cellular-resolution genomewide gene expression map for low-abundance Arabidopsis thaliana organ boundary cells and constructed a genomewide protein-DNA interaction map focusing on genes affecting boundary and AM formation. The resulting GRN uncovers transcriptional signatures, predicts cellular functi

SUBMITTER: Tian C 

PROVIDER: S-EPMC4299377 | biostudies-literature | 2014 Oct

REPOSITORIES: biostudies-literature