Ontology highlight
ABSTRACT:
SUBMITTER: Park M
PROVIDER: S-EPMC4345276 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Park Minhwa M Kim Yu-Hee YH Ryu Jung-Hwa JH Woo So-Youn SY Ryu Kyung-Ha KH
Stem cells international 20150216
Mesenchymal stem cells (MSCs) are considered valuable sources for cell therapy because of their immune regulatory function. Here, we investigated the effects of tonsil-derived MSCs (T-MSCs) on the differentiation, maturation, and function of dendritic cells (DCs). We examined the effect of T-MSCs on differentiation and maturation of bone-marrow- (BM-) derived monocytes into DCs and we found suppressive effect of T-MSCs on DCs via direct contact as well as soluble mediators. Moreover, T cell prol ...[more]