Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia.
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ABSTRACT:
SUBMITTER: van Luijn MM
PROVIDER: S-EPMC4353169 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Publications
Class II-associated invariant chain peptide as predictive immune marker in minimal residual disease in acute myeloid leukemia.
van Luijn Marvin M MM van den Ancker Willemijn W van Ham S Marieke SM van de Loosdrecht Arjan A AA
Oncoimmunology 20141201 12
The majority of patients with acute myeloid leukemia (AML) reach complete remission after high-dose chemotherapy. Still, half of these patients experience a relapse due to presence of minimal residual disease (MRD). Here we discuss the poor prognostic role of class II-associated invariant chain peptide (CLIP) expression on residual leukemic cells. ...[more]
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