Ontology highlight
ABSTRACT:
SUBMITTER: Xie Z
PROVIDER: S-EPMC4382248 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Xie Zhongwen Z Su Wen W Liu Shu S Zhao Guogang G Esser Karyn K Schroder Elizabeth A EA Lefta Mellani M Stauss Harald M HM Guo Zhenheng Z Gong Ming Cui MC
The Journal of clinical investigation 20141208 1
As the central pacemaker, the suprachiasmatic nucleus (SCN) has long been considered the primary regulator of blood pressure circadian rhythm; however, this dogma has been challenged by the discovery that each of the clock genes present in the SCN is also expressed and functions in peripheral tissues. The involvement and contribution of these peripheral clock genes in the circadian rhythm of blood pressure remains uncertain. Here, we demonstrate that selective deletion of the circadian clock tra ...[more]