Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study.
Ontology highlight
ABSTRACT: Background
Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma.Methods
We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study.Results
Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend=0.02). Associations were observed among men, but not women.Conclusions
Prolonged occupational exposure to endocrine disruptors seems to be moderately associated with some lymphoma subtypes.
SUBMITTER: Costas L
PROVIDER: S-EPMC4385964 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Publications
Occupational exposure to endocrine disruptors and lymphoma risk in a multi-centric European study.
Costas L L Infante-Rivard C C Zock J-P JP Van Tongeren M M Boffetta P P Cusson A A Robles C C Casabonne D D Benavente Y Y Becker N N Brennan P P Foretova L L Maynadié M M Staines A A Nieters A A Cocco P P de Sanjosé S S
British journal of cancer 20150331 7
<h4>Background</h4>Incidence rates of lymphoma are usually higher in men than in women, and oestrogens may protect against lymphoma.<h4>Methods</h4>We evaluated occupational exposure to endocrine disrupting chemicals (EDCs) among 2457 controls and 2178 incident lymphoma cases and subtypes from the European Epilymph study.<h4>Results</h4>Over 30 years of exposure to EDCs compared to no exposure was associated with a 24% increased risk of mature B-cell neoplasms (P-trend=0.02). Associations were o ...[more]
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