Effect of intravenous iron use on hospitalizations in patients undergoing hemodialysis: a comparative effectiveness analysis from the DEcIDE-ESRD study.

ABSTRACT:

Background

Intravenous iron use in hemodialysis patients has greatly increased over the last decade, despite limited studies on the safety of iron.

Methods

We studied the association of receipt of intravenous iron with hospitalizations in an incident cohort of hemodialysis patients. We examined 9544 patients from Dialysis Clinic, Inc. (DCI). We ascertained intravenous iron use from DCI electronic medical record and USRDS data files, and hospitalizations through Medicare claims. We examined the association between iron exposure accumulated over 1-, 3- or 6-month time windows and incident hospitalizations in the follow-up period using marginal structural models accounting for time-dependent confounders. We performed sensitivity analyses including recurrent events models for mu

SUBMITTER: Tangri N 

PROVIDER: S-EPMC4402378 | biostudies-literature | 2015 Apr

REPOSITORIES: biostudies-literature